You can fix this problem by switching your copy of Office 2010 from a Click-to-Run installation to a standard (MSI-based) installation.
Unfortunately, this virtual environment prohibits Zotero from communicating with these Word instances, producing an error. Microsoft distributes a set of “Click-to-Run” versions of Office 2010 that are configured to run within their own virtual environment.
You may be experiencing an issue relating to your Word 2010 installation method. “Zotero experienced an error updating your document. If you install Zotero with Word 2010 and receive an error stating
